Actuated Medical, Inc. designs, develops, and manufactures medical devices for clearing occlusions, penetrating bone and tissue, and enabling the emerging MRI–guided surgical procedure industry. The company offers occlusion clearing systems, such as TubeClear, a mechanical motion technology that clears clogs for nasoenteral small bore feeding tubes. It also provides controlled tissue penetration systems, such as GentleSharp Device for pre-clinical veterinary and laboratory research applications; OsteoAccess System that uses controlled, micron-scale vibration to penetrate bone at a non-90 degree access with reduced force; and GentleDispense System that uses a low power-activated, needle-free patch for transdermal delivery of large molecule compounds.

In addition, the company offers magnetic resonance imaging compatible systems, such as direct drive piezoelectric ultrasonic motors. Actuated Medical, Inc. was formerly known as Piezo Resonance Innovations, Inc. and changed its name to Actuated Medical, Inc. in September 2011. The company was founded in 2006 and is based in Bellefonte, Pennsylvania.